All times Central
| TIME | GAME | TV | LINE |
| 11:00 | Michigan St. at Northwestern |
 |
MSU -6 |
| 11:00 | Syracuse at West Virginia |
 |
WVU -13.5 |
| 11:00 | Penn St. at Minnesota |
 |
PSU -9 |
| 11:00 | Purdue at Ohio St. |
 |
OSU -23.5 |
| 11:00 | Iowa St. at Texas |
 |
TX -20.5 |
| 11:00 | Notre Dame vs Navy |
 |
ND -6.5 |
| 2:30 | Wisconsin at Iowa1 |  |
IA -6 |
| 2:30 | Nebraska at Oklahoma St.1 | |
NU -6 |
| 2:30 | Georgia Tech at Clemson1 | |
CLEM -5.5 |
| 2:30 | LSU at Auburn |
|
AUB -5.5 |
| 2:30 | Houston at SMU |
 |
SMU -8.5 |
| 2:30 | Connecticut at Louisville |
|
UL -3 |
| 6:00 | Arizona St. at Cal |
|
CAL -3 |
| 6:00 | Alabama at Tennessee |  |
BAMA -16 |
| 6:00 | Texas A&M at Kansas |
|
A&M -14 |
| 6:00 |
UAB at Mississippi St. |
|
MSU -19.5 |
| 6:30 | UNC at Miami |
|
MIA -7 |
| 7:00 | Oklahoma at Missouri |
|
OU -3 |
| 7:00 | Air Force at TCU |
|
TCU -18.5 |
| 9:15 | Washington at Arizona |
|
AZ -6.5 |
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