All times Central
| TIME | GAME | TV | LINE |
| 11:00 | Iowa at Northwestern |
 |
IA -10 |
| 11:00 | Indiana at Wisconsin |
 |
WISC -21.5 |
| 11:00 | South Florida at Louisville |
 |
UL -2.5 |
| 11:00 | Michigan at Purdue |
 |
MICH -13 |
| 11:00 | Ole Miss at Tennessee |
 |
TN -2.5 |
| 11:30 | Kansas St. at Missouri |
 |
MU -13 |
| 1:30 | Utah at Notre Dame |
 |
UT -5.5 |
| 2:30 | Penn St. at Ohio St.MAP |  |
OSU -18 |
| 2:30 | Texas Tech at OklahomaMAP | |
OU -15 |
| 2:30 | Virginia Tech at North CarolinaMAP | |
UNC -3.5 |
| 2:30 | Georgia at Auburn |
|
AUB -6.5 |
| 2:30 | Syracuse at Rutgers |
|
SYR -2.5 |
| 3:00 | San Diego St. at TCU |
 |
TCU -27 |
| 6:00 | South Carolina at Florida |
 |
UF -6.5 |
| 6:00 | Texas A&M at Baylor |
|
A&M -3 |
| 6:00 |
UTEP at Arkansas |
|
AR -28.5 |
| 6:15 | Mississipi St. at Alabama |
|
BAMA -13.5 |
| 6:30 | Oregon at California |
|
ORE -19.5 |
| 7:00 | USC at ArizonaMAP |
|
AZ -4.5 |
| 7:00 | Clemson at Florida StateMAP |
|
FSU -5.5 |
| 7:00 | Oklahoma St. at TexasMAP |
|
OSU -5.5 |
| 7:00 | Tulsa at Houston |
 |
UH -2.5 |
| 9:30 | Nevada at Fresno St. |
|
NEV -8 |
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