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Thursday, October 24
| Matchup | Time (CT) | TV | Streaming |
|---|---|---|---|
| Matchup | Time (CT) | TV | Streaming |
| #16 SMU at Houston | 6:30 PM | ESPN | WatchESPN.com |
Friday, October 25
| Matchup | Time (CT) | TV | Streaming |
|---|---|---|---|
| Matchup | Time (CT) | TV | Streaming |
| USC at Colorado | 8:00 PM | ESPN2 | WatchESPN.com |
Saturday, October 26
| Matchup | Time (CT) | TV | Streaming |
|---|---|---|---|
| Matchup | Time (CT) | TV | Streaming |
| #13 Wisconsin at #3 Ohio State | 11:00 AM | FOX | FoxSportsGo.com |
| #5 Oklahoma at Kansas State | 11:00 AM | ABC | WatchESPN.com |
| #20 Iowa at Northwestern | 11:00 AM | ESPN2 | WatchESPN.com |
| #21 Appalachian State at South Alabama | 11:00 AM | ESPNU | WatchESPN.com |
| Miami at Pittsburgh | 11:00 AM | ESPN | WatchESPN.com |
| San Jose State at Army | 11:00 AM | CBSSN | CBSSports.com |
| Mississippi State at Texas A&M | 11:00 AM | SEC Network | WatchESPN.com |
| Illinois at Purdue | 11:00 AM | BTN | FoxSportsGo.com |
| Liberty at Rutgers | 11:00 AM | BTN | FoxSportsGo.com |
| Bowling Green at Western Michigan | 11:00 AM | ESPN3 | WatchESPN.com |
| Southern Mississippi at Rice | 12:00 PM | ESPN+ | ESPN+ |
| Nevada at Wyoming | 1:00 PM | AT&T Sportsnet | TheMW.com |
| Ohio at Ball State | 1:00 PM | ESPN+ | ESPN+ |
| Western Kentucky at Marshall | 1:30 PM | None | |
| New Mexico State at Georgia Southern | 2:00 PM | ESPN3 | WatchESPN.com |
| #9 Auburn at #2 LSU | 2:30 PM | CBS | CBSSports.com |
| #6 Penn State at Michigan State | 2:30 PM | ABC | WatchESPN.com |
| #15 Texas at TCU | 2:30 PM | FOX | FoxSportsGo.com |
| Maryland at #17 Minnesota | 2:30 PM | ESPN | WatchESPN.com |
| Oklahoma State at #23 Iowa State | 2:30 PM | FS1 | FoxSportsGo.com |
| UConn at UMass | 2:30 PM | NESN | FloFootball.com |
| North Texas at Charlotte | 2:30 PM | ESPN+ | ESPN+ |
| Florida International at Middle Tennessee | 2:30 PM | NFL | NFLNetwork.com |
| Florida Atlantic at Old Dominion | 2:30 PM | ESPN+ | ESPN+ |
| Syracuse at Florida State | 2:30 PM | ESPN2 | WatchESPN.com |
| Virginia at Louisville | 2:30 PM | ACC Network | WatchESPN.com |
| Arizona at Stanford | 2:30 PM | Pac-12 Networks | Pac-12.com |
| Indiana at Nebraska | 2:30 PM | BTN | FoxSportsGo.com |
| Tulane at Navy | 2:30 PM | CBSSN | CBSSports.com |
| Central Michigan at Buffalo | 2:30 PM | ESPN+ | ESPN+ |
| Eastern Michigan at Toledo | 2:30 PM | ESPN+ | ESPN+ |
| Miami (OH) at Kent State | 2:30 PM | ESPN+ | ESPN+ |
| Akron at Northern Illinois | 2:30 PM | ESPN3 | WatchESPN.com |
| South Florida at East Carolina | 2:45 PM | ESPNU | WatchESPN.com |
| Hawai'i at New Mexico | 3:00 PM | Spectrum Sports | |
| Duke at North Carolina | 3:00 PM | ACCNX | WatchESPN.com |
| South Carolina at Tennessee | 3:00 PM | SEC Network | WatchESPN.com |
| Arkansas at #1 Alabama | 6:00 PM | ESPN | WatchESPN.com |
| Texas Tech at Kansas | 6:00 PM | FS1 | FoxSportsGo.com |
| UCF at Temple | 6:00 PM | ESPN2 | WatchESPN.com |
| Memphis at Tulsa | 6:00 PM | CBSSN | CBSSports.com |
| Texas State at Arkansas State | 6:00 PM | ESPN+ | ESPN+ |
| Troy at Georgia State | 6:00 PM | ESPN+ | ESPN+ |
| Boston College at #4 Clemson | 6:30 PM | ACC Network | WatchESPN.com |
| #8 Notre Dame at #19 Michigan | 6:30 PM | ABC | WatchESPN.com |
| #24 Arizona State at UCLA | 6:30 PM | Pac-12 Networks | Pac-12.com |
| Colorado State at Fresno State | 6:30 PM | ESPNU | WatchESPN.com |
| Missouri at Kentucky | 6:30 PM | SEC Network | WatchESPN.com |
| Louisiana Tech at UTEP | 7:00 PM | ESPN3 | WatchESPN.com |
| California at #12 Utah | 9:00 PM | FS1 | FoxSportsGo.com |
| Utah State at Air Force | 9:15 PM | ESPN2 | WatchESPN.com |
| Washington State at #11 Oregon | 9:30 PM | ESPN | WatchESPN.com |
| San Diego State at UNLV | 9:30 PM | CBSSN | CBSSports.com |